Evidence Based Clinical Guidelines

The following evidence based clinical guidelines have been compiled and reviewed by CHAMPS staff for use by Region VIII health center clinicians.  CHAMPS performs an extensive search of clinical guidelines and selects those that are most relevant to the work of Region VIII health centers from the highest quality sources.  These guidelines are intended to be used as a reference to clinical care, at the discretion of the clinician.  Guidelines on this page are reviewed and updated annually.   If you utilize an evidence based clinical guideline(s) appropriate for health center clinicians that is not listed on this webpage, please contact the CHAMPS Clinical Quality Improvement Director.

Please click or scroll down for:
Evidence Based Clinical Guidelines by Disease/Condition
Links to Evidence Based Clinical Guideline Databases


Acute Otitis Media

The Diagnosis and Management of Acute Otitis Media
American Academy of Pediatrics
February 2013

Antibiotics for Acute Respiratory Infections

Antibiotics, Appropriate Use for Acute Respiratory Infections
December 2007


See Evidence Based Clinical Guidelines on the Asthma Treatment Resources webpage

Behavioral Health

See Evidence Based Clinical Guidelines on the Behavioral Health Resources webpage

Birth Weight (Low)

See Evidence Based Clinical Guidelines on the Women’s Reproductive Health Resources webpage

Cardiovascular Disease

Adult CVD and Stroke Prevention Guideline
April 2012

Cardiovascular Guidelines
Institute for Clinical Systems Improvement (ICSI)
Diagnosis and Initial Treatment of Ischemic Stroke
Diagnosis and Treatment of Chest Pain and Acute Coronary Syndrome (ACS)
Heart Failure in Adults
Hypertension Diagnosis and Treatment
Lipid Management in Adults
Stable Coronary Artery Disease

Focused Update of the Guideline for the Diagnosis and Management of Patients with Stable Ischemic Heart Disease
American College of Cardiology (ACC), American Heart Association (AHA), American Association for Thoracic Surgery (AATS), Preventive Cardiovascular Nurses Association (PCNA), Society for Cardiovascular Angiography and Interventions (SCAI), and Society of Thoracic Surgeons (STS)
July 2014

Guideline on the Assessment of Cardiovascular Risk: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
November 2013

Guideline on Lifestyle Management to Reduce Cardiovascular Risk
July 2014

Guideline for the Management of Patients with Atrial Fibrillation
ACC, AHA, and Heart Rhythm Society (HRS)
March 2014

Cervical Cancer

See Evidence Based Clinical Guidelines on the Women’s Reproductive Health Resources webpage

Chronic Pain

See Evidence Based Clinical Guidelines on the Resources for Treating Patients with Chronic Pain webpage

Colorectal Cancer

Colorectal Cancer Screening Guideline
February 2009

Screening for Colorectal Cancer
U.S. Preventive Services Task Force (USPSTF)
June 2016

Contraception/Family Planning

Contraception Guideline
January 2011

U.S. Selected Practice Recommendations for Contraceptive Use, 2013
Centers for Disease Control and Prevention (CDC)
June 2013

Preconception and Interconception Care Guideline
December 2009

Providing Quality Family Planning Services: Recommendations of the CDC and U.S. Office of Population Affairs
April 2014

Chronic Obstructive Pulmonary Disease (COPD)

Diagnosis and Management of Stable Chronic Obstructive Pulmonary Disease: A Clinical Practice Guideline Update
American College of Physicians, American College of Chest Physicians, American Thoracic Society, and European Respiratory Society
August 2011


See Evidence Based Clinical Guidelines on the Diabetes Treatment Resources webpage

Gestational Diabetes

Gestational Diabetes Guideline
November 2006 (Addendum April 2009)

Screening for Gestational Diabetes Mellitus
January 2014

Hepatitis B and C

Guidelines on Hepatitis B and C Testing
World Health Organization (WHO)
February 2017


See Evidence Based Clinical Guidelines on the HIV/AIDS Treatment Resources webpage


Immunization Recommendations
CDC, Advisory Committee on Immunization Practices (ACIP)
Current Recommendations and Schedules

Obesity – Adults and Children

See Evidence Based Clinical Guidelines on the Overweight and Obesity Treatment and Prevention Resources webpage

Opioid Use Disorder

See Evidence Based Clinical Guidelines on the Opioid Use Disorder Resources webpage

Oral Health

See Evidence Based Clinical Guidelines on the Oral Health Resources webpage


Pharmacological Management of Osteoporosis in Postmenopausal Women: An Endocrine Society Clinical Practice Guideline
The Journal of Clinical Endocrinology & Metabolism
March 2019

Screening for Osteoporosis to Prevent Fractures
June 2018

Screening for Osteoporosis in the Adult U.S. Population
American College of Preventive Medicine (ACPM)

Ovarian Cancer

The Recognition and Initial Management of Ovarian Cancer
National Institute for Health and Clinical Excellence (NHS)

Pancreatic Cancer

Final Recommendation Statement: Pancreatic Cancer Screening
U.S. Preventive Services Task Force

Physical Activity

2018 Physical Activity Guidelines for Americans
U.S.  Department of Health and Human Services (HHS)

Global Recommendations on Physical Activity for Health
World Health Organization (WHO)

Quantity and Quality of Exercise for Developing and Maintaining Cardiorespiratory, Musculoskeletal, and Neuromotor Fitness in Apparently Health Adults:  Guidance for Prescribing Exercise
American College of Sports Medicine
July 2011

Prenatal Care

See Evidence Based Clinical Guidelines on the Women’s Reproductive Health Resources webpage

Prevention/Health Maintenance

Clinical Preventive Health Recommendations for General and Targeted Populations Guideline
February 2014

Summary of Recommendations for Clinical Preventive Services
American Academy of Family Physicians (AAFP)
July 2014

The Guide to Clinical Preventive Services
USPSTF and Agency for Healthcare Research and Quality (AHRQ)

Sexually Transmitted Disease

Sexually Transmitted Diseases
American Family Physician (AFP)
Compilation of guidelines updated August 2014

Substance Use

See Evidence Based Clinical Guidelines on the Substance Use Resources webpage

Tobacco Cessation

See Evidence Based Clinical Guidelines on the Tobacco Cessation Resources webpage


Cochrane Summaries

Access to evidence based information to assist consumers and health care providers in making decisions about health

Formerly Colorado Clinical Guidelines Collaborative (CCGC), originally founded to convene stakeholders to create evidence based clinical guidelines for Colorado providers

Institute for Clinical Systems Improvement (ICSI)
Championing the use of evidence based medicine, ICSI enlists clinicians from its membership to perform rigorous review of current literature and develop guidelines and protocols on numerous health conditions

Guidelines and Measures (GAM) – Agency for Healthcare Research and Quality (AHRQ)
Public resource for evidence based clinical practice guidelines

SAMHSA’s Evidence-Based Practices Resource Center
Searchable online registry of more than 330 substance abuse and mental health interventions

Trip Database
A tool to help users find high-quality clinical research evidence